A Metabolic Pathway Driving Growth of Aggressive Lung Cancers
نویسندگان
چکیده
منابع مشابه
The Role of Mammalian Target of Rapamycine Signaling Pathway in Central Nervous System Cancers: A Review
Mammalian mechanistic target of rapamycine (mTOR) is a conserved serine/threonine kinase in the cellular PI3K/Akt/mTOR signaling pathway. This pathway is modified by cellular alterations such as level of energy, growth factors, stresses, as well as the increased environmental level of cancerous cytokines. In general, increase of this kinase protein function is seen in various types of cancers, ...
متن کاملNestin: A biomarker of aggressive uterine cancers.
OBJECTIVE Evidence of potential prognostic and predictive value for nestin was investigated in well-annotated uterine cancers (UCs). METHODS Nestin expression and previously-published biomarkers were evaluated by immunohistochemistry (IHC) in UC tissue microarrays. Biomarkers were categorized as low vs. high, and nestin was cut at 10% positive staining. Relationship between nestin and clinico...
متن کاملAutomobile Driving And Aggressive Behavior
Automobile driving and aggressive behavior have had an extensive association. Themes of dominance and territoriality have long been part of automobile driving, which has aLso involved flagrant assaultive actions. Recent episodes of roadway violence in metropolitan areas have raised community concem about aggressive behavior in driving, although common beliefs about why such violence occurs can ...
متن کاملDriving citations and aggressive behavior.
BACKGROUND Anger and driving have been examined in a number of studies of aggressive drivers and in drivers with road rage using various psychological and environmental study variables. However, we are not aware of any study that has examined the number of driving citations (an indication of problematic driving) and various forms of anger not related to driving. METHOD Using a cross-sectional...
متن کاملCysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth
The relevance of cysteine metabolism in cancer has gained considerable interest in recent years, largely focusing on its role in generating the antioxidant glutathione. Through metabolomic profiling using a combination of high-throughput liquid and gas chromatography-based mass spectrometry on a total of 69 patient-derived glioma specimens, this report documents the discovery of a parallel path...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oncology Times
سال: 2021
ISSN: 0276-2234
DOI: 10.1097/01.cot.0000749936.14046.87